Dr. Tao Wang talks about his recent Nature Communications publication, in which he leverages the IMPC and Mutagenetix data to estimate the probability of phenotypically detectable protein damage predicted by various mutation effect prediction algorithms. His work further applied these estimated probabilities in addressing interesting questions in mouse genetics. Dr. Wang also talks about his related research in cancer genomics.
Nature Communications article: https://www.nature.com/articles/s41467-017-02806-4
Tao Wang’s lab: http://www.utsouthwestern.edu/labs/wang-tao/
Mutagenetix database https://www.nature.com/articles/s41467-017-02806-4